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| Date | Location | Result | |
| 2/19/22 | St. Joseph, MN | Saint Benedict 61, St. Scholastica 33 | Box score |
| 2/16/22 | Northfield, MN | St. Olaf 67, St. Scholastica 59 | Box score |
| 2/14/22 | Duluth, MN (Reif Gym) | St. Scholastica 57, Concordia (MN) 53 | Box score |
| 2/12/22 | Saint Peter, MN | Gustavus Adolphus 68, St. Scholastica 45 | Box score |
| 3/9/22 | Duluth, MN (Reif Gym) | Bethel 79, St. Scholastica 38 | Box score |
| 2/7/22 | Duluth, MN (Reif Gym) | St. Scholastica 68, Macalester 57 | Box score |
| 2/5/22 | Duluth, MN (Reif Gym) | Carleton 58, St. Scholastica 42 | Box score |
| 2/2/22 | Saint Paul, MN | Hamline 61, St. Scholastica 35 | Box score |
| 1/29/22 | Winona, MN | Saint Mary's 72, St. Scholastica 68 | Box score |
| 1/26/22 | Duluth, MN (Reif Gym) | St. Scholastica 61, St. Catherine 55 | Box score |
| 1/22/22 | St. Joseph, MN | Saint Benedict 64, St. Scholastica 60 | Box score |
| 1/19/22 | Minneapolis, MN | Augsburg 74, St. Scholastica 39 | Box score |
| 1/15/22 | Duluth, MN (Reif Gym) | Gustavus Adolphus 77, St. Scholastica 53 | Box score |
| 1/12/22 | Duluth, MN (Reif Gym) | St. Olaf 67, St. Scholastica 55 | Box score |
| 1/10/22 | St. Paul, MN | Bethel 96, St. Scholastica 46 | Box score |
| 1/8/22 | Moorhead, MN | Concordia (MN) 76, St. Scholastica 47 | Box score |
| 1/5/22 | Duluth, MN (Reif Gym) | Hamline 68, St. Scholastica 59 | Box score |
| 12/11/21 | Northfield, MN | Carleton 76, St. Scholastica 52 | Box score |
| 12/8/21 | Saint Paul, MN | Macalester 69, St. Scholastica 48 | Box score |
| 12/4/21 | Duluth, MN (Reif Gym) | Saint Mary's 65, St. Scholastica 57 | Box score |
| 12/2/21 | Duluth, MN (Reif Gym) | Augsburg 82, St. Scholastica 55 | Box score |
| 11/23/21 | Saint Paul, MN | St. Catherine 75, St. Scholastica 52 | Box score |
| 11/20/21 | Duluth, MN (Reif Gym) | Saint Benedict 61, St. Scholastica 49 | Box score |
| 11/17/21 | Duluth, MN (Reif Gym) | UW-Superior 71, St. Scholastica 45 | Box score |
| 11/10/21 | Saint Bonifacius, MN | Crown 86, St. Scholastica 76 | Box score |